First step of the calculator, with the patient's details and the switches for liver disease, fenbendazole and nutritional guidance
First page of the PDF document generated by the calculator

Ivermectin dose calculator, with optional fenbendazole

A dose without a source
is a dose in the dark.

In the tables that circulate, nobody says which article the number came from, the presentation is not the one sold in Brazil and there is no schedule of lab tests. The calculator does the opposite: dose by weight, the source next to every number and the monitoring plan, in a PDF that the health professional takes to the medical record and the patient takes to the appointment, always with professional follow-up.

Launch: US$ 15, one-time payment, lifetime access. After the launch, US$ 60.

Payment through Stripe. No subscription, no card stored on this site.

A number without an origin serves
neither the health professional nor the patient.

In drug repurposing, dose tables without a source circulate, along with schedules copied from forums and two drugs with different regulatory status treated as if they were one. The risk is not only the wrong dose: it is not knowing where it came from.

  • 01

    Doses without provenance

    Ready-made tables say how much to take, but not which article or trial the number came from, nor whether it was tested in people or only in animal models.

  • 02

    Two drugs, two statuses

    Ivermectin is used outside its registered indication (off-label). Fenbendazole has no registration for human use with ANVISA and exists only in veterinary presentations in Brazil. Mixing the two hides that difference.

  • 03

    Conversion error

    The 222 mg sachet from the foreign literature contains 1 gram of granules at 22.2% and is not sold in Brazil. Confusing 1 g with 222 mg gets the dose wrong by 4.5 times.

  • 04

    No monitoring plan

    In a case report of severe liver injury from self-medication with fenbendazole, symptoms began 7 days after the dose was increased to daily (PMID 41608149). Whoever starts without a baseline test and without a collection schedule finds out late.

None of this replaces the health professional. The document exists to move the conversation with them onto the ground of sources.

Four steps.
Every choice with the source next to it.

The calculator is a step by step. Each step shows only its own choices, with the provenance right below the selector, and the last one gathers everything before generating the document.

Outside the weight and age ranges nothing is generated: outside them there is no bibliographic support.

Calculator step 1 of 4
01

Patient details

Name (goes only to the document's identification), weight from 30 to 200 kg, age from 18 to 100 years, established liver disease and the switches that include fenbendazole and the nutritional guidance.

02

Ivermectin parameters

Target dose among 5 levels with provenance, from 0.4 to 2.0 mg/kg, and the weekly schedule: 3 consecutive days, as in the registered trials, or daily. The start is gradual: 0.2 and 0.3 mg/kg before the target dose.

03

Fenbendazole parameters optional

222 or 444 mg per day, the same for all weight ranges, converted to the 100 mg/mL suspension sold in Brazil and compared with the 500 mg double-scored tablet.

04

Review and document

Summary of the choices, consolidated alerts, doses per phase and the button that generates the PDF on the server. No patient data is stored.

A PDF that explains itself.

Twelve sections with fenbendazole, ten without, counting the nutritional guidance, which is included by default. From the header to the legal notice, the patient and the health professional read the same document, with the same sources.

The sections, in the order they come out

  1. 1.Identification
  2. 2.Dose calculation summary - Ivermectin
  3. 3.Protocol 1 - Combined (Ivermectin + Fenbendazole) fenbendazole only
  4. 4.Protocol 2 - Ivermectin alone (monotherapy)
  5. 5.Comparison table - Protocol 1 vs. Protocol 2 fenbendazole only
  6. 6.Administration rules
  7. 7.Consideration by age range
  8. 8.Monitoring and safety
  9. 9.Nutritional guidance to support treatment optional
  10. 10.Glossary of acronyms and terms
  11. 11.Scientific references
  12. 12.Legal notice

Without fenbendazole, its sections are removed and the numbering closes from 1 to 10, with no gap. The header becomes "Ivermectin - Drug Repurposing". The nutritional guidance is included by default; the health professional can leave it out, and the numbering adjusts.

  • Provenance printed next to every dose

    Which article, trial registration or practice convention the number comes from. Where there is no source, it says so.

  • Weekly calendar and administration rules

    The days of each drug in the week, taking with food and the presentations sold in Brazil.

  • Monitoring with 5 tests and suspension criteria

    Baseline, week 4, week 6 and then every 8 weeks for liver function; stopping thresholds in plain text.

  • Glossary with 47 terms and 18 references with links

    Acronyms explained inside the document and articles indexed in PubMed, with a clickable PMID.

A4, selectable text, clickable PubMed links, generated on the server from the same choices as the review. The screen and the document use the same calculation.

Pages of the sample document

Generated for a fictional patient, 72 kg and 58 years old, with fenbendazole. The nutritional guidance pages are left out of this preview (see the next section). Selectable text and clickable links in the real PDF.

A diet without a source
is a diet in the dark.

Every food list going around contradicts the last one, and none says where it came from. The document's nutritional guidance follows the rule of the rest of the PDF: its basis with the PMID alongside and the gap stated where there is no source. It comes in the same file the health professional takes to the medical record and the patient takes to the appointment, always with professional follow-up.

01

What comes off the plate

The food groups to remove, each with its reason.

02

How to build meals

The balance between food groups and the preferred sources of each.

03

When to eat

At what times to eat and how that fits the dose schedule.

04

How to cook and follow up

How to prepare food and what to measure to follow up.

First page of the nutritional guidance in the sample document, with the content blurred on purpose
First page of the guidance in the sample document, blurred in this preview.

What the calculator does not do is as important as what it does.

It does not prescribe, does not adjust the dose on its own and does not hide a gap. Every limit is stated in text, on screen and in the document.

3 safety alerts

Triggered at the step where the choice is made and repeated in the document, right after the identification:

  • Declared liver disease with a dose above the range with preclinical support
  • Fenbendazole at 444 mg/day - doubled weekly exposure
  • Daily schedule selected - weekly exposure more than double that of the trials

No alert changes the dose on its own: the professional decides, the calculator informs.

5 monitored tests

The document's monitoring table, with frequency and action criterion for each row:

  • AST / ALT / GGT
  • Total bilirubin
  • Complete blood count
  • Serum calcium
  • 25-OH Vitamin D3

Liver schedule: baseline, week 4, week 6 and then every 8 weeks. Above 3 times the upper limit of normal, immediate suspension.

Transparency note

Where there is no source, the document says so. The liver schedule is safety reasoning around the first escalation of ivermectin, not a transcription of a specific source, and it is declared as such in the PDF. No dose is estimated or inferred.

Consideration by age range

From 18 to 60 years, from 61 to 74 and from 75 on: each range gets its own note in the document, with the liver care and the limitation of data in the very elderly written out in full.

Provenance of 0.4 mg/kg, the default target dose

Human equivalent of the median dose used in the studies in animal tumor models (5 mg/kg, range 2.4 to 40 mg/kg) - Juarez 2018, PMID 29511601. It is also the dose of the high-dose arm of the ICONIC trial (NCT07487805), no results yet. There is preclinical evidence of an antitumor mechanism (Melotti 2014, PMID 25143352; Hashimoto 2009, PMID 22495656); the effective dose in patients has not been established in a clinical trial.

Fixed notice of the calculator, reproduced in the document

There is preclinical evidence of an antitumor mechanism for ivermectin and fenbendazole (see references). What is not established is the effective dose in patients: no completed clinical trial has defined an ivermectin dose in cancer.

For those who conduct the treatment and for those who follow it closely.

Anyone can purchase access. What changes is the use: the professional decides, the patient talks to the one who decides.

For health professionals

Health professionals who need a document with sources for the medical record and for the conversation with the patient.

  • Five target-dose levels with provenance (Juarez 2018, Guzzo 2002, Buonfrate 2022), instead of a percentage scale of the maximum tolerated dose, which does not exist in this context.
  • Two published weekly schedules: 3 consecutive days, as in trials NCT05318469 and NCT07487805, or daily, with the difference in weekly exposure made explicit.
  • Conversion to 6 mg and 3 mg human tablets and to the Brazilian presentations of fenbendazole: 100 mg/mL suspension and 500 mg double-scored tablet.
  • Monitoring table, suspension criteria and alerts in the same text the document prints: what you read on screen is what the patient takes with them.

For patients and caregivers

Those who follow the treatment closely and want to understand, with sources, what is being discussed with the health professional.

  • Use it with guidance from a health professional: the document does not prescribe, does not replace the appointment and does not decide anything on its own.
  • Take the document to the health professional who follows you: it shows where each number comes from, which tests to follow and when to stop.
  • Glossary with 47 terms to understand acronyms such as ULN, AST and PMID without leaving the PDF.
  • Your data is not kept: name, weight and age exist only while the document is generated.

US$ 15 today.
Lifetime access.

While the launch lasts, lifetime access costs US$ 15 in a one-time payment. When the launch ends, the same access goes to US$ 60.

Launch offer
US$ 15US$ 60final price after the launch

one-time payment · lifetime access

Get lifetime access for US$ 15

Payment processed by Stripe, by card, in US dollars.

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  • Lifetime access to the calculator, with no renewal and no subscription
  • Complete PDF document: 12 sections, 18 references, glossary and legal notice
  • Optional fenbendazole, with the presentations sold in Brazil
  • Nutritional guidance to support treatment, in the same PDF
  • 3 safety alerts and monitoring table with 5 tests
  • Email support

Why US$ 15?

The launch is meant to put the document in the hands of those who need it now and to listen to those who use it. That is why the entry price is a fraction of the final price.

There is no announced date for the end of the launch. When it ends, the price changes here and at checkout, and whoever already secured access pays no difference.

In numbers

Everything here can be checked in the document.

references indexed in PubMed
18
sections in the document
12
terms in the glossary
47
dose levels with provenance
5

2 weekly schedules · 3 safety alerts · 5 monitored tests · weight from 30 to 200 kg · age from 18 to 100 years

  • No patient data is stored
  • PDF generated on the server, with selectable text and clickable links
  • Sources: PubMed, trial registrations and regulatory agencies

Frequently asked
questions

From professionals and from patients. If yours is not here, write to faq@ivercalc.com.

Dr. Carlos
Founder and CEO

Dr. Carlos

@drcarlosaname

Biomedical scientist, specialist in functional medicine and nutrition.

With a postgraduate degree in Aesthetic Biomedicine, he furthered his studies in Nutritional Adequacy and Maintenance of Endocrine Homeostasis: Prevention and Treatment of Age-Related Diseases, by Dr. Lair Ribeiro.

He starts from functional physiology and biochemistry to understand each patient. In metabolic health, he reads epigenetics and metabolism to reach the origin of the imbalance. In aesthetic biomedicine, he treats beauty as a reflection of health. In bio-oxidative and regenerative therapies, he works with the body's own capacity to regenerate. In everything, the same principle: investigate the cause before treating the symptom.

At Base Funcional, he brings together in one place the apps, courses and e-books that take functional medicine from investigating the cause to the daily routine of the practice.

US$ 15, one-time payment, lifetime access. After the launch, US$ 60.